[www.ncbi.nlm.nih.gov]

Presence of compounds such as limonene, selinene, frocoumarin glycosides, flavonoids, and vitamins A and C are the reason that celery is the most widely used plant in traditional medicine.20

Celery can prevent cardiovascular diseases,21 jaundice, liver and lien diseases,22 urinary tract obstruction,18 gout,22 and rheumatic disorders.23 Research on rats shows that ethanol extracts of celery leaves increases spermatogenesis24 and also improves their fertility.15,25,26 Celery reduces glucose, blood lipids,7,27 and blood pressure, which can strengthen the heart.28 Experimental studies show that celery has antifungal29 and anti-inflammatory properties.30 Moreover, its essential oils have antibacterial effects.31 Its seeds are useful in the treatment of bronchitis,22 asthenopia, asthma, chronic skin disorders, including psoriasis,32 vomiting, fever, and tumors.33 The root of the celery is diuretic and it is used for the treatment of colic.33 Plants are an important source of natural active products, which vary, based on mechanism and biological properties. Various phytochemical compounds, especially polyphenols (such as flavonoids, phenolic acids, and tansipropanoids) are responsible for collecting free radicals and antioxidant activities of plants.34 Polyphenols have biological effects. These effects, especially the antioxidant activities, are inductors for restraining free radicals and peroxidation. Polyphenols generally exhibit similar chemical properties, which means that one or more number of the phenolic groups can react with hydrogen donors and neutralize free radicals.35

Phenolic and antioxidant compounds of celery have been studied by several scientists.36 Celery root and its leaves have the property to remove OH and DPPH (2,2-diphenyl-1-picrylhydrazyl) radicals and the plant also reduces the intensity of liposomal peroxidation that represents the plant’s protection.37

Celery, because of compounds such as caffeic acid, p-coumaric acid, ferulic acid, apigenin, luteolin, tannin, saponin, and kaempferol, has powerful antioxidant characteristics, while different compounds of this plant with diverse concentration can have different healing effects.