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Link between Parkinson’s disease and crop-protecting chemicals
Posted by: Panchito ()
Date: November 26, 2013 11:52PM


"The rats in a room at the University of Pittsburgh regularly get hit with doses of pesticide. But the researchers in J. Timothy Greenamyre’s lab don’t expose the rodents because of an infestation problem. They give the neurotoxin to the animals to learn more about Parkinson’s disease.

After receiving a low daily dose of the pesticide rotenone for a week or two, rats in Greenamyre’s lab begin to lose mobility in ways similar to Parkinson’s patients. The rodents move at a glacial pace, they have trouble keeping their balance, and their limbs become impossibly stiff. Even the animals’ brains develop classic signs of the nervous system disorder: Nerve cells in a region called the substantia nigra accumulate clumps of the protein synuclein and die.

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