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Hospitalizations for heart conditions, neurological illness, and other conditions were higher among people who live near unconventional gas and oil drilling (hydraulic fracturing), according to new research from the University of Pennsylvania and Columbia University published this week in PLOS ONE. Over the past ten years in the United States, hydraulic fracturing has experienced a meteoric increase. Due to substantial increases in well drilling, potential for air and water pollution posing a health threat has been a concern for nearby residents.

To address this issue, researchers from two Environmental Health Science Core Centers (EHSCC) of the National Institute of Environmental Health Sciences -- the Center of Excellence in Environmental Toxicology (CEET) at Penn’s Perelman School of Medicine and the Center for Environmental Health in Northern Manhattan at the Mailman School of Public Health, Columbia University, examined the link between drilling well density and healthcare use by zip code from 2007 to 2011 in three northeastern Pennsylvania counties.

Using databases that contained over 198,000 hospitalizations (which includes multiple hospitalizations for the same person), the team examined the top 25 specific medical categories for hospitalizations, as defined by the Pennsylvania Health Cost Containment Council. They associated these categories with residents’ proximity to active wells. Two of the counties -- Bradford and Susquehanna -- saw a significant increase in drilling activity over this time period, while the control county, Wayne, experienced no drilling activity due to a ban on drilling in that county because of its proximity to the Delaware River watershed.

“This study captured the collective response of residents to hydraulic fracturing in zip codes within the counties with higher well densities,” said senior author Reynold Panettieri, Jr., MD, a professor of Medicine and CEET deputy director. “At this point, we suspect that residents are exposed to many toxicants, noise, and social stressors due to hydraulic fracturing near their homes and this may add to the increased number of hospitalizations. This study represents one of the most comprehensive to date to link health effects with hydraulic fracturing.”

However, the authors caution that more study is needed to determine how specific, individual toxicants or combinations may increase hospitalization rates. For example, the increase in cardiology hospitalizations could be related to an increased exposure to air pollution such as diesel exhaust and fine particulate matter; however, this would require personal monitoring studies to measure exposure to specific toxicants, Panettieri notes. “Our findings provide important clues to design epidemiological studies to associate specific toxicant exposures with health end-points.”

Their findings revealed that cardiology and neurologic inpatient prevalence rates (the proportion of a population found to have been hospitalized per 100 residents per year) were significantly higher in areas closer to active wells, as determined by the proximity of wells to a person’s home and their density as defined by the number of active wells per square kilometer. In addition, increased neurologic inpatient prevalence rates were associated with higher well density. Hospitalizations for skin conditions, cancer, and urologic problems were also associated with the proximity of dwellings to active wells.