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Long term dangers of high protein diets
Posted by: Panchito ()
Date: June 02, 2022 09:43PM


Diet which is high in protein generates a large amount of acid in body fluids [2]. The kidneys respond to this dietary acid challenge with net acid excretion, and, concurrently, the skeleton supplies buffer by active resorption of bone resulting in excessive calcium loss [2]. Moreover, acid loading directly inhibits renal calcium reabsorption leading to hypercalciuria in combination with the exorbitant bone loss [3, 4]. In a metabolic study an increase in protein intake from about 47 to 112 g caused an increase in urinary calcium and a decrease in calcium retention. The data indicated that protein-induced hypercalciuria was due to an elevation in glomerular filtration rate and a lower fractional renal tubular reabsorption of calcium, the latter of which caused by the increased acid load on the renal tubular cells [8]

Low fluid intake and excessive intake of protein are important risk factors for kidney stones [3]. Protein ingestion increases renal acid excretion, and acid loads, in turn, may be buffered in part by bone, which releases calcium to be excreted by the kidney. This protein-induced hypercalciuria could lead to the formation of calcium kidney stones [4]. Furthermore, animal protein is also the major dietary source of purines, the precursors of uric acid. Excessive intake of animal protein is therefore associated with hyperuricosuria, a condition present in some uric acid stone formers [5]. Uric acid solubility is largely determined by the urinary pH. As the pH falls below 5.5 to 6.0, the solubility of uric acid decreases, and uric acid precipitates, even if hyperuricosuria is not present [5].

Up to 80% of breast, bowel, and prostate cancers are attributed to dietary practices, and international comparisons show positive associations with high meat diet [6]. The association, however, seems to have been more consistently found for red meat or processed meat and colorectal cancer [7]. Possible mechanisms include the formation of heterocyclic amines in meat when it is cooked. These heterocyclic amines require acetylation by P450 enzymes, and individuals with the fast-acetylating genotype who eat high amounts of meat may be at increased risk of large-bowel cancer [6]. It should be noticed that red meat is the main dietary source of saturated fat, which has been associated with breast and colorectal cancers [1].

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Re: Long term dangers of high protein diets
Posted by: Horsea ()
Date: June 02, 2022 11:26PM

Somebody ought to send your info to the Weston Price Foundation. They are fixated on animal food because of its high concentration of nutrients, not understanding that there is a point of diminishing returns in all "good" things.

For women who don't nurse their babies, they even have a substitute containing pureed raw liver. OY. DISGUSTING.

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Re: Long term dangers of high protein diets
Posted by: ReubenT ()
Date: June 03, 2022 05:56PM

Horse owners know that horses need around 10% protein for maintenance. Young growing animals or mares with foals can use more. Too much protein is hard on their kidneys they say. I have assumed people are similar. But for some reason that point of info hasn't made it into the human health info very well. Sometimes industry financial gain stops appropriate health info from getting through.

I have heard those who eat too much plant based processed proteins such as vegetarian meat substitutes can have similar health issues caused by meat eating. that plus the expense of them has made me stick to mostly simple plant based diet without overdoing any one thing. Adding a little milk and eggs for variety.

Weston Price may have the wrong idea on meat eating. But they have an excellent article introducing nutrient dense fertility management which is the way to go in growing super healthy nutritious food. []

Edited 1 time(s). Last edit at 06/03/2022 06:05PM by ReubenT.

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